Imagine the Taliban (and its al Qaeda brothers) with nuclear weapons. That is the goal of the Jihadist movement, the assassination of Benazir Bhutto was but one step along the road towards that goal: http://www.opinionjournal.com/editorial/feature.html?id=110011053.
The Wall Street Journal has it exactly right. Blame has been leveled at Pakistani President Pervez Musharraf for Bhutto's assassination, and Bhutto herself had written an e-mail just days before her death in which she apparently said that Musharraf should receive the blame in the event that she was killed. Logically, though, and ironically, Musharraf is the one with the most to lose by what happened yesterday, and like him or not, trust him or not, he is no dummy. He realized that. As facts continue to come out, I may be proven wrong, but I would be very, very surprised if he was behind the assassination.
On the other hand, the instability created by Bhutto's death benefits the Islamofascists (and their many supporters in the Pakistani military apparatus). The more unstable the Pakistani government becomes, the more likely it is that an Islamist could end up in charge of the country and its nuclear weapons. That would and should concern everyone in the West, and equally importantly, it would cause a lot of concern in the country directly to the east of Pakistan, India. You can be sure that New Delhi is watching the goings on in Pakistan with great concern, and don't be surprised to see an increase in the military preparedness of the Indian Army. As well, I wouldn't be shocked if there were some kind of plan put into place to seize the Pakistani nukes in the event of an Islamofascist takeover of the country.